Vitamin D receptor–retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation
Identifieur interne : 002650 ( Main/Exploration ); précédent : 002649; suivant : 002651Vitamin D receptor–retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation
Auteurs : Alerie Guzman De La Fuente ; Oihana Errea ; Peter Van Wijngaarden ; Ginez A. Gonzalez ; Christophe Kerninon ; Andrew A. Jarjour ; Hilary J. Lewis ; Clare A. Jones ; Brahim Nait-Oumesmar ; Chao Zhao ; Jeffrey K. Huang ; Charles Ffrench-Constant ; Robin J. M. FranklinSource :
- The Journal of Cell Biology [ 0021-9525 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Animaux, Cellules souches (cytologie), Différenciation cellulaire, Femelle, Gaine de myéline (), Humains, Liaison aux protéines, Lignage cellulaire, Multimérisation de protéines, Mâle, Oligodendroglie (cytologie), Rat Sprague-Dawley, Rats, Récepteur X des rétinoïdes type gamma (métabolisme), Récepteur calcitriol (métabolisme), Régulation de l'expression des gènes, Sclérose en plaques (métabolisme), Sujet âgé, Sujet âgé de 80 ans ou plus, Transduction du signal, Vitamine D (métabolisme).
- MESH :
- cytologie : Cellules souches, Oligodendroglie.
- métabolisme : Récepteur X des rétinoïdes type gamma, Récepteur calcitriol, Sclérose en plaques, Vitamine D.
- Adulte, Adulte d'âge moyen, Animaux, Différenciation cellulaire, Femelle, Gaine de myéline, Humains, Liaison aux protéines, Lignage cellulaire, Multimérisation de protéines, Mâle, Rat Sprague-Dawley, Rats, Régulation de l'expression des gènes, Sujet âgé, Sujet âgé de 80 ans ou plus, Transduction du signal.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Animals, Cell Differentiation, Cell Lineage, Female, Gene Expression Regulation, Humans, Male, Middle Aged, Multiple Sclerosis (metabolism), Myelin Sheath (chemistry), Oligodendroglia (cytology), Protein Binding, Protein Multimerization, Rats, Rats, Sprague-Dawley, Receptors, Calcitriol (metabolism), Retinoid X Receptor gamma (metabolism), Signal Transduction, Stem Cells (cytology), Vitamin D (metabolism).
- MESH :
- chemical , metabolism : Receptors, Calcitriol, Retinoid X Receptor gamma, Vitamin D.
- chemistry : Myelin Sheath.
- cytology : Oligodendroglia, Stem Cells.
- metabolism : Multiple Sclerosis.
- Adult, Aged, Aged, 80 and over, Animals, Cell Differentiation, Cell Lineage, Female, Gene Expression Regulation, Humans, Male, Middle Aged, Protein Binding, Protein Multimerization, Rats, Rats, Sprague-Dawley, Signal Transduction.
Abstract
Activation of retinoid X receptor γ and vitamin D receptor (VDR) heterodimer via vitamin D enhances oligodendrocyte progenitor differentiation, whereas blocking VDR impairs differentiation and myelination ex vivo.
Url:
DOI: 10.1083/jcb.201505119
PubMed: 26644513
PubMed Central: 4674280
Affiliations:
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Le document en format XML
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Zhang</name></author><author><name sortKey="Chen, K" uniqKey="Chen K">K. Chen</name></author><author><name sortKey="Sloan, S A" uniqKey="Sloan S">S.A. Sloan</name></author><author><name sortKey="Bennett, M L" uniqKey="Bennett M">M.L. Bennett</name></author><author><name sortKey="Scholze, A R" uniqKey="Scholze A">A.R. Scholze</name></author><author><name sortKey="O Eeffe, S" uniqKey="O Eeffe S">S. O’Keeffe</name></author><author><name sortKey="Phatnani, H P" uniqKey="Phatnani H">H.P. Phatnani</name></author><author><name sortKey="Guarnieri, P" uniqKey="Guarnieri P">P. Guarnieri</name></author><author><name sortKey="Caneda, C" uniqKey="Caneda C">C. Caneda</name></author><author><name sortKey="Ruderisch, N" uniqKey="Ruderisch N">N. Ruderisch</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="De La Fuente, Alerie Guzman" sort="De La Fuente, Alerie Guzman" uniqKey="De La Fuente A" first="Alerie Guzman" last="De La Fuente">Alerie Guzman De La Fuente</name><name sortKey="Errea, Oihana" sort="Errea, Oihana" uniqKey="Errea O" first="Oihana" last="Errea">Oihana Errea</name><name sortKey="Ffrench Constant, Charles" sort="Ffrench Constant, Charles" uniqKey="Ffrench Constant C" first="Charles" last="Ffrench-Constant">Charles Ffrench-Constant</name><name sortKey="Franklin, Robin J M" sort="Franklin, Robin J M" uniqKey="Franklin R" first="Robin J. M." last="Franklin">Robin J. M. Franklin</name><name sortKey="Gonzalez, Ginez A" sort="Gonzalez, Ginez A" uniqKey="Gonzalez G" first="Ginez A." last="Gonzalez">Ginez A. Gonzalez</name><name sortKey="Huang, Jeffrey K" sort="Huang, Jeffrey K" uniqKey="Huang J" first="Jeffrey K." last="Huang">Jeffrey K. Huang</name><name sortKey="Jarjour, Andrew A" sort="Jarjour, Andrew A" uniqKey="Jarjour A" first="Andrew A." last="Jarjour">Andrew A. Jarjour</name><name sortKey="Jones, Clare A" sort="Jones, Clare A" uniqKey="Jones C" first="Clare A." last="Jones">Clare A. Jones</name><name sortKey="Kerninon, Christophe" sort="Kerninon, Christophe" uniqKey="Kerninon C" first="Christophe" last="Kerninon">Christophe Kerninon</name><name sortKey="Lewis, Hilary J" sort="Lewis, Hilary J" uniqKey="Lewis H" first="Hilary J." last="Lewis">Hilary J. Lewis</name><name sortKey="Nait Oumesmar, Brahim" sort="Nait Oumesmar, Brahim" uniqKey="Nait Oumesmar B" first="Brahim" last="Nait-Oumesmar">Brahim Nait-Oumesmar</name><name sortKey="Van Wijngaarden, Peter" sort="Van Wijngaarden, Peter" uniqKey="Van Wijngaarden P" first="Peter" last="Van Wijngaarden">Peter Van Wijngaarden</name><name sortKey="Zhao, Chao" sort="Zhao, Chao" uniqKey="Zhao C" first="Chao" last="Zhao">Chao Zhao</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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